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IRE1 (ERN1) Human Gene Knockout Kit (CRISPR)

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SKU
KN215023RB
ERN1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

RC215023 ERN1 (Myc-DDK-tagged)-Human endoplasmic reticulum to nucleus signaling 1 (ERN1)
10 ug
$1,341.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "IRE1 or NM_001433"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol IRE1
Locus ID 2081
Components

KN215023G1, IRE1 gRNA vector 1 in pCas-Guide CRISPR vector

KN215023G2, IRE1 gRNA vector 2 in pCas-Guide CRISPR vector

KN215023RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001433, NM_152461
UniProt ID O75460
Synonyms hIRE1p; IRE1; IRE1a; IRE1P
Summary This gene encodes the transmembrane protein kinase inositol-requiring enzyme 1. The encoded protein contains two functional catalytic domains, a serine/threonine-protein kinase domain and an endoribonuclease domain. This protein functions as a sensor of unfolded proteins in the endoplasmic reticulum (ER) and triggers an intracellular signaling pathway termed the unfolded protein response (UPR). The UPR is an ER stress response that is conserved from yeast to mammals and activates genes involved in degrading misfolded proteins, regulating protein synthesis and activating molecular chaperones. This protein specifically mediates the splicing and activation of the stress response transcription factor X-box binding protein 1. provided by RefSeq, Aug 2017
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Other Versions
SKU Description Size Price
GA101455 ERN1 CRISPRa kit - CRISPR gene activation of human endoplasmic reticulum to nucleus signaling 1 1 kit
$1,657.00
KN215023 ERN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215023BN ERN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215023LP ERN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN415023 ERN1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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