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Human IRE1 (ERN1) activation kit by CRISPRa

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SKU
GA101455
ERN1 CRISPRa kit - CRISPR gene activation of human endoplasmic reticulum to nucleus signaling 1
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC215023 ERN1 (Myc-DDK-tagged)-Human endoplasmic reticulum to nucleus signaling 1 (ERN1)
10 ug
$1,341.00

Other products for "ERN1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ERN1
Locus ID 2081
Components

GA101455G1, IRE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101455G2, IRE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101455G3, IRE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001433, NM_152461
UniProt ID O75460
Synonyms hIRE1p; IRE1; IRE1a; IRE1P
Summary This gene encodes the transmembrane protein kinase inositol-requiring enzyme 1. The encoded protein contains two functional catalytic domains, a serine/threonine-protein kinase domain and an endoribonuclease domain. This protein functions as a sensor of unfolded proteins in the endoplasmic reticulum (ER) and triggers an intracellular signaling pathway termed the unfolded protein response (UPR). The UPR is an ER stress response that is conserved from yeast to mammals and activates genes involved in degrading misfolded proteins, regulating protein synthesis and activating molecular chaperones. This protein specifically mediates the splicing and activation of the stress response transcription factor X-box binding protein 1. provided by RefSeq, Aug 2017
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Documents
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Other Versions
SKU Description Size Price
KN215023 ERN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215023BN ERN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215023LP ERN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215023RB ERN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN415023 ERN1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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