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PGC1 alpha (PPARGC1A) Human Gene Knockout Kit (CRISPR)

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SKU
KN212244RB
PPARGC1A - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "PGC1 alpha or NM_001330751"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol PGC1 alpha
Locus ID 10891
Components

KN212244G1, PGC1 alpha gRNA vector 1 in pCas-Guide CRISPR vector

KN212244G2, PGC1 alpha gRNA vector 2 in pCas-Guide CRISPR vector

KN212244RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001330751, NM_001330752, NM_001330753, NM_013261, NM_001354825, NM_001354826, NM_001354827, NM_001354828, NR_148981, NR_148982, NR_148983, NR_148984, NR_148985, NR_148986, NR_148987
UniProt ID Q9UBK2
Synonyms LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1
Summary The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA107462 PPARGC1A CRISPRa kit - CRISPR gene activation of human PPARG coactivator 1 alpha 1 kit
$1,657.00
KN212244 PPARGC1A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN212244BN PPARGC1A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN212244LP PPARGC1A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN412244 PPARGC1A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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