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CTLA4 Human Gene Knockout Kit (CRISPR)

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SKU
KN210150BN
CTLA4 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "CTLA4 or NM_001037631"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol CTLA4
Locus ID 1493
Components

KN210150G1, CTLA4 gRNA vector 1 in pCas-Guide CRISPR vector

KN210150G2, CTLA4 gRNA vector 2 in pCas-Guide CRISPR vector

KN210150BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001037631, NM_005214
UniProt ID P16410
Synonyms ALPS5; CD; CD152; CELIAC3; CTLA-4; GRD4; GSE; IDDM12
Summary This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA101056 CTLA4 CRISPRa kit - CRISPR gene activation of human cytotoxic T-lymphocyte associated protein 4 1 kit
$1,657.00
KN210150 CTLA4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN210150LP CTLA4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN210150RB CTLA4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN410150 CTLA4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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