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Human CTLA4 activation kit by CRISPRa

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SKU
GA101056
CTLA4 CRISPRa kit - CRISPR gene activation of human cytotoxic T-lymphocyte associated protein 4
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA810299 CTLA4 mouse monoclonal antibody,clone OTI1G10 100 ul
$447.00
RC213631 CTLA4 (Myc-DDK-tagged)-Human cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 2
10 ug
$450.00

Other products for "CTLA4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CTLA4
Locus ID 1493
Components

GA101056G1, CTLA4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101056G2, CTLA4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101056G3, CTLA4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001037631, NM_005214
UniProt ID P16410
Synonyms ALPS5; CD; CD152; CELIAC3; CTLA-4; GRD4; GSE; IDDM12
Summary This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN210150 CTLA4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN210150BN CTLA4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN210150LP CTLA4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN210150RB CTLA4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN410150 CTLA4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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