SOX9 Human Gene Knockout Kit (CRISPR)

SKU KN208944BN

SOX9 - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Vector: mBFP-Neo
• Target Symbol: SOX9
• Locus ID: 6662
• Components:

  KN208944G1, SOX9 gRNA vector 1 in pCas-Guide CRISPR vector

  KN208944G2, SOX9 gRNA vector 2 in pCas-Guide CRISPR vector

  KN208944BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_000346
• UniProt ID: P48436
• Synonyms: CMD1; CMPD1; SRA1; SRXX2; SRXY10
• Summary: The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. [provided by RefSeq, Jul 2008]
• Shipping: Ambient