Human SOX9 activation kit by CRISPRa

SKU GA104571

SOX9 CRISPRa kit - CRISPR gene activation of human SRY-box transcription factor 9

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SOX9
• Locus ID: 6662
• Components:

  GA104571G1, SOX9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104571G2, SOX9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104571G3, SOX9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000346
• UniProt ID: P48436
• Synonyms: CMD1; CMPD1; SRA1; SRXX2; SRXY10
• Summary: The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. [provided by RefSeq, Jul 2008]