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ApoER2 (LRP8) Human Gene Knockout Kit (CRISPR)

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SKU
KN208674RB
LRP8 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "ApoER2 or NM_001018054"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol ApoER2
Locus ID 7804
Components

KN208674G1, ApoER2 gRNA vector 1 in pCas-Guide CRISPR vector

KN208674G2, ApoER2 gRNA vector 2 in pCas-Guide CRISPR vector

KN208674RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001018054, NM_004631, NM_017522, NM_033300
UniProt ID Q14114
Synonyms APOER2; HSZ75190; LRP-8; MCI1
Summary This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Jun 2011
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Other Versions
SKU Description Size Price
GA105321 LRP8 CRISPRa kit - CRISPR gene activation of human LDL receptor related protein 8 1 kit
$1,657.00
KN208674 LRP8 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208674BN LRP8 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208674LP LRP8 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN408674 LRP8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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