WNT7B Human Gene Knockout Kit (CRISPR)

CAT#: KN207691RB

WNT7B - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: WNT7B
• Locus ID: 7477
• Components:

  KN207691G1, WNT7B gRNA vector 1 in pCas-Guide CRISPR vector

  KN207691G2, WNT7B gRNA vector 2 in pCas-Guide CRISPR vector

  KN207691RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_058238
• UniProt ID: P56706
• Synonyms: wingless-type MMTV integration site family, member 7B
• Summary: This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein. [provided by RefSeq, Oct 2008]