AXL Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
|---|---|
| Vector | mBFP-Neo |
| Target Symbol | AXL |
| Locus ID | 558 |
| Components |
KN206431G1, AXL gRNA vector 1 in pCas-Guide CRISPR vector KN206431G2, AXL gRNA vector 2 in pCas-Guide CRISPR vector KN206431BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001278599, NM_001699, NM_021913 |
| UniProt ID | P30530 |
| Synonyms | ARK; JTK11; Tyro7; UFO |
| Summary | The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. provided by RefSeq, Jul 2013 |
| Shipping | Ambient |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA100385 | AXL CRISPRa kit - CRISPR gene activation of human AXL receptor tyrosine kinase | 1 kit |
$1,657.00
|
|
| KN206431 | AXL - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN206431LP | AXL - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN206431RB | AXL - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN406431 | AXL - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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