Human AXL activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | AXL |
| Locus ID | 558 |
| Components |
GA100385G1, AXL gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100385G2, AXL gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100385G3, AXL gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001278599, NM_001699, NM_021913 |
| UniProt ID | P30530 |
| Synonyms | ARK; JTK11; Tyro7; UFO |
| Summary | The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. provided by RefSeq, Jul 2013 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN206431 | AXL - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN206431BN | AXL - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN206431LP | AXL - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN206431RB | AXL - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN406431 | AXL - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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