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CYP1A1 Human Gene Knockout Kit (CRISPR)

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SKU
KN205760LP
CYP1A1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "CYP1A1 or NM_000499"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol CYP1A1
Locus ID 1543
Components

KN205760G1, CYP1A1 gRNA vector 1 in pCas-Guide CRISPR vector

KN205760G2, CYP1A1 gRNA vector 2 in pCas-Guide CRISPR vector

KN205760LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000499, NM_001319216, NM_001319217
UniProt ID P04798
Synonyms AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX
Summary This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Jan 2016
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Documents
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Other Versions
SKU Description Size Price
GA101090 CYP1A1 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 1 subfamily A member 1 1 kit
$1,657.00
KN205760 CYP1A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205760BN CYP1A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205760RB CYP1A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405760 CYP1A1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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