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Human CYP1A1 activation kit by CRISPRa

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SKU
GA101090
CYP1A1 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 1 subfamily A member 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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Other products for "CYP1A1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CYP1A1
Locus ID 1543
Components

GA101090G1, CYP1A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101090G2, CYP1A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101090G3, CYP1A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000499, NM_001319216, NM_001319217
UniProt ID P04798
Synonyms AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX
Summary This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Jan 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN205760 CYP1A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205760BN CYP1A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205760LP CYP1A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205760RB CYP1A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405760 CYP1A1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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