RAB18 Human Gene Knockout Kit (CRISPR)

SKU KN205505RB

RAB18 - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Vector: RFP-BSD
• Target Symbol: RAB18
• Locus ID: 22931
• Components:

  KN205505G1, RAB18 gRNA vector 1 in pCas-Guide CRISPR vector

  KN205505G2, RAB18 gRNA vector 2 in pCas-Guide CRISPR vector

  KN205505RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001256410, NM_001256411, NM_001256412, NM_001256415, NM_021252, NR_046172, N56901
• UniProt ID: Q9NP72
• Synonyms: RAB18LI1; WARBM3
• Summary: The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
• Shipping: Ambient