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CD46 Human Gene Knockout Kit (CRISPR)

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SKU
KN205384LP
CD46 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "CD46 or NM_002389"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol CD46
Locus ID 4179
Components

KN205384G1, CD46 gRNA vector 1 in pCas-Guide CRISPR vector

KN205384G2, CD46 gRNA vector 2 in pCas-Guide CRISPR vector

KN205384LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_002389, NM_153826, NM_172350, NM_172351, NM_172352, NM_172353, NM_172354, NM_172355, NM_172356, NM_172357, NM_172358, NM_172359, NM_172360, NM_172361
UniProt ID P15529
Synonyms AHUS2; MCP; MIC10; TLX; TRA2.10
Summary The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. provided by RefSeq, Jun 2010
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Other Versions
SKU Description Size Price
GA102850 CD46 CRISPRa kit - CRISPR gene activation of human CD46 molecule 1 kit
$1,657.00
KN205384 CD46 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205384BN CD46 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205384RB CD46 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405384 CD46 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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