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Human CD46 activation kit by CRISPRa

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SKU
GA102850
CD46 CRISPRa kit - CRISPR gene activation of human CD46 molecule
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA349781 Rabbit Polyclonal Anti-CD46 Antibody
100 ul
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RC222198 CD46 (Myc-DDK-tagged)-Human CD46 molecule, complement regulatory protein (CD46), transcript variant n
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Other products for "CD46"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CD46
Locus ID 4179
Components

GA102850G1, CD46 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102850G2, CD46 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102850G3, CD46 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_002389, NM_153826, NM_172350, NM_172351, NM_172352, NM_172353, NM_172354, NM_172355, NM_172356, NM_172357, NM_172358, NM_172359, NM_172360, NM_172361
UniProt ID P15529
Synonyms AHUS2; MCP; MIC10; TLX; TRA2.10
Summary The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. provided by RefSeq, Jun 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN205384 CD46 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205384BN CD46 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205384LP CD46 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN205384RB CD46 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN405384 CD46 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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