OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

PRAME Human Gene Knockout Kit (CRISPR)

Be the first to review this product
SKU
KN204142BN
PRAME - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

TA333925 Rabbit Polyclonal Anti-PRAME Antibody
100 ul
$585.00
RC214243 PRAME (Myc-DDK-tagged)-Human preferentially expressed antigen in melanoma (PRAME), transcript variant 1
10 ug
$474.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "PRAME or NM_001291715"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol PRAME
Locus ID 23532
Components

KN204142G1, PRAME gRNA vector 1 in pCas-Guide CRISPR vector

KN204142G2, PRAME gRNA vector 2 in pCas-Guide CRISPR vector

KN204142BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001291715, NM_001291716, NM_001291717, NM_001291719, NM_001318126, NM_001318127, NM_006115, NM_206953, NM_206954, NM_206955, NM_206956
UniProt ID P78395
Synonyms CT130; MAPE; OIP-4; OIP4
Summary This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. provided by RefSeq, Apr 2014
Shipping Ambient
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
GA108375 PRAME CRISPRa kit - CRISPR gene activation of human preferentially expressed antigen in melanoma 1 kit
$1,657.00
KN204142 PRAME - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204142LP PRAME - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204142RB PRAME - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404142 PRAME - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products