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Human PRAME activation kit by CRISPRa

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SKU
GA108375
PRAME CRISPRa kit - CRISPR gene activation of human preferentially expressed antigen in melanoma
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA333925 Rabbit Polyclonal Anti-PRAME Antibody
100 ul
$585.00
RC214243L2V Lenti ORF particles, PRAME (mGFP-tagged) - Human preferentially expressed antigen in melanoma (PRAME), transcript variant 1, 200ul, >10^7 TU/mL
200 ul
$1,024.00

Other products for "PRAME"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PRAME
Locus ID 23532
Components

GA108375G1, PRAME gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108375G2, PRAME gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108375G3, PRAME gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001291715, NM_001291716, NM_001291717, NM_001291719, NM_001318126, NM_001318127, NM_006115, NM_206953, NM_206954, NM_206955, NM_206956
UniProt ID P78395
Synonyms CT130; MAPE; OIP-4; OIP4
Summary This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. provided by RefSeq, Apr 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN204142 PRAME - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204142BN PRAME - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204142LP PRAME - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204142RB PRAME - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404142 PRAME - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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