PRAME (NM_006115) Human Tagged ORF Clone Lentiviral Particle

SKU RC214243L2V

Lenti ORF particles, PRAME (mGFP-tagged) - Human preferentially expressed antigen in melanoma (PRAME), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: PRAME
• Synonyms: CT130; MAPE; OIP-4; OIP4
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214243).
• ACCN: NM_006115
• ORF Size: 1527 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_006115.3, NP_006106.1
• RefSeq Size: 2162 bp
• RefSeq ORF: 1530 bp
• Locus ID: 23532
• UniProt ID: P78395
• Cytogenetics: 22q11.22
• MW: 57.7 kDa
• Summary: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]