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ALIX (PDCD6IP) Human Gene Knockout Kit (CRISPR)

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SKU
KN203735RB
PDCD6IP - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "ALIX or NM_001162429"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol ALIX
Locus ID 10015
Components

KN203735G1, ALIX gRNA vector 1 in pCas-Guide CRISPR vector

KN203735G2, ALIX gRNA vector 2 in pCas-Guide CRISPR vector

KN203735RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001162429, NM_001256192, NM_013374, NR_027867, NR_027868
UniProt ID Q8WUM4
Synonyms AIP1; ALIX; DRIP4; HP95
Summary This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. provided by RefSeq, Jan 2012
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Documents
Resources
Other Versions
SKU Description Size Price
GA106783 PDCD6IP CRISPRa kit - CRISPR gene activation of human programmed cell death 6 interacting protein 1 kit
$1,657.00
KN203735 PDCD6IP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203735BN PDCD6IP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203735LP PDCD6IP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403735 PDCD6IP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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