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Human ALIX (PDCD6IP) activation kit by CRISPRa

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SKU
GA106783
PDCD6IP CRISPRa kit - CRISPR gene activation of human programmed cell death 6 interacting protein
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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$447.00
RC203735 PDCD6IP (Myc-DDK-tagged)-Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1
10 ug
$795.00

Other products for "PDCD6IP"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PDCD6IP
Locus ID 10015
Components

GA106783G1, ALIX gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106783G2, ALIX gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106783G3, ALIX gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001162429, NM_001256192, NM_013374, NR_027867, NR_027868
UniProt ID Q8WUM4
Synonyms AIP1; ALIX; DRIP4; HP95
Summary This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. provided by RefSeq, Jan 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN203735 PDCD6IP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203735BN PDCD6IP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203735LP PDCD6IP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203735RB PDCD6IP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403735 PDCD6IP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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