OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

ALIX (PDCD6IP) Human Gene Knockout Kit (CRISPR)

Be the first to review this product
SKU
KN203735BN
PDCD6IP - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

TA507312 PDCD6IP mouse monoclonal antibody, clone OTI1A4 (formerly 1A4) 100 ul
$447.00
RC203735 PDCD6IP (Myc-DDK-tagged)-Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1
10 ug
$795.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "ALIX or NM_001162429"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol ALIX
Locus ID 10015
Components

KN203735G1, ALIX gRNA vector 1 in pCas-Guide CRISPR vector

KN203735G2, ALIX gRNA vector 2 in pCas-Guide CRISPR vector

KN203735BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001162429, NM_001256192, NM_013374, NR_027867, NR_027868
UniProt ID Q8WUM4
Synonyms AIP1; ALIX; DRIP4; HP95
Summary This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. provided by RefSeq, Jan 2012
Shipping Ambient
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
GA106783 PDCD6IP CRISPRa kit - CRISPR gene activation of human programmed cell death 6 interacting protein 1 kit
$1,657.00
KN203735 PDCD6IP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203735LP PDCD6IP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203735RB PDCD6IP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403735 PDCD6IP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products