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NRAS Human Gene Knockout Kit (CRISPR)

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SKU
KN202681LP
NRAS - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "NRAS or NM_002524"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol NRAS
Locus ID 4893
Components

KN202681G1, NRAS gRNA vector 1 in pCas-Guide CRISPR vector

KN202681G2, NRAS gRNA vector 2 in pCas-Guide CRISPR vector

KN202681LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_002524
UniProt ID P01111
Synonyms ALPS4; CMNS; N-ras; NCMS; NRAS1; NS6
Summary This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. provided by RefSeq, Jun 2011
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Documents
Resources
Other Versions
SKU Description Size Price
GA103268 NRAS CRISPRa kit - CRISPR gene activation of human NRAS proto-oncogene, GTPase 1 kit
$1,657.00
KN202681 NRAS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202681BN NRAS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202681RB NRAS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402681 NRAS - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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