Human NRAS activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | NRAS |
| Locus ID | 4893 |
| Components |
GA103268G1, NRAS gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103268G2, NRAS gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103268G3, NRAS gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_002524 |
| UniProt ID | P01111 |
| Synonyms | ALPS4; CMNS; N-ras; NCMS; NRAS1; NS6 |
| Summary | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. provided by RefSeq, Jun 2011 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN202681 | NRAS - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN202681BN | NRAS - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN202681LP | NRAS - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN202681RB | NRAS - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN402681 | NRAS - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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