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KRAS Human Gene Knockout Kit (CRISPR)

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SKU
KN201958RB
KRAS - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "KRAS or NM_004985"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol KRAS
Locus ID 3845
Components

KN201958G1, KRAS gRNA vector 1 in pCas-Guide CRISPR vector

KN201958G2, KRAS gRNA vector 2 in pCas-Guide CRISPR vector

KN201958RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_004985, NM_033360, NM_001369786, NM_001369787
UniProt ID P01116
Synonyms C-K-RAS; c-Ki-ras2; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS; NS3; RALD
Summary This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA102608 KRAS CRISPRa kit - CRISPR gene activation of human KRAS proto-oncogene, GTPase 1 kit
$1,657.00
KN201958 KRAS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201958BN KRAS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201958LP KRAS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401958 KRAS - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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