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Beta Arrestin 2 (ARRB2) Human Gene Knockout Kit (CRISPR)

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SKU
KN201168BN
ARRB2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

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Other products for "Beta Arrestin 2 or NM_001257328"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol Beta Arrestin 2
Locus ID 409
Components

KN201168G1, Beta Arrestin 2 gRNA vector 1 in pCas-Guide CRISPR vector

KN201168G2, Beta Arrestin 2 gRNA vector 2 in pCas-Guide CRISPR vector

KN201168BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001257328, NM_001257329, NM_001257330, NM_001257331, NM_004313, NM_199004, NR_047516, NM_001330064
UniProt ID P32121
Synonyms ARB2; ARR2; BARR2
Summary Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Mar 2012
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Other Versions
SKU Description Size Price
GA100298 ARRB2 CRISPRa kit - CRISPR gene activation of human arrestin beta 2 1 kit
$1,657.00
KN201168 ARRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201168LP ARRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201168RB ARRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401168 ARRB2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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