Human Beta Arrestin 2 (ARRB2) activation kit by CRISPRa

SKU
GA100298
ARRB2 CRISPRa kit - CRISPR gene activation of human arrestin beta 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ARRB2
Locus ID 409
Components

GA100298G1, Beta Arrestin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100298G2, Beta Arrestin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100298G3, Beta Arrestin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001257328, NM_001257329, NM_001257330, NM_001257331, NM_004313, NM_199004, NR_047516, NM_001330064
UniProt ID P32121
Synonyms ARB2; ARR2; BARR2
Summary Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Mar 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN201168 ARRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201168BN ARRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201168LP ARRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201168RB ARRB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401168 ARRB2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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