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Superoxide Dismutase 1 (SOD1) Human Gene Knockout Kit (CRISPR)

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SKU
KN200725LP
SOD1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "Superoxide Dismutase 1 or NM_000454"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Superoxide Dismutase 1
Locus ID 6647
Components

KN200725G1, Superoxide Dismutase 1 gRNA vector 1 in pCas-Guide CRISPR vector

KN200725G2, Superoxide Dismutase 1 gRNA vector 2 in pCas-Guide CRISPR vector

KN200725LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000454
UniProt ID P00441
Synonyms ALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD
Summary The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. provided by RefSeq, Jul 2020
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Other Versions
SKU Description Size Price
GA104557 SOD1 CRISPRa kit - CRISPR gene activation of human superoxide dismutase 1 1 kit
$1,657.00
KN200725 SOD1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200725BN SOD1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200725RB SOD1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400725 SOD1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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