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ERK5 (MAPK7) Human Gene Knockout Kit (CRISPR)

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SKU
KN200655LP
MAPK7 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "ERK5 or NM_002749"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol ERK5
Locus ID 5598
Components

KN200655G1, ERK5 gRNA vector 1 in pCas-Guide CRISPR vector

KN200655G2, ERK5 gRNA vector 2 in pCas-Guide CRISPR vector

KN200655LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_002749, NM_139032, NM_139033, NM_139034
UniProt ID Q13164
Synonyms BMK1; ERK4; ERK5; PRKM7
Summary The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA103788 MAPK7 CRISPRa kit - CRISPR gene activation of human mitogen-activated protein kinase 7 1 kit
$1,657.00
KN200655 MAPK7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200655BN MAPK7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200655RB MAPK7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400655 MAPK7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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