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Integrin beta 4 binding protein (EIF6) Human Gene Knockout Kit (CRISPR)

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SKU
KN200568RB
EIF6 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "Integrin beta 4 binding protein or NM_001267810"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Integrin beta 4 binding protein
Locus ID 3692
Components

KN200568G1, Integrin beta 4 binding protein gRNA vector 1 in pCas-Guide CRISPR vector

KN200568G2, Integrin beta 4 binding protein gRNA vector 2 in pCas-Guide CRISPR vector

KN200568RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001267810, NM_002212, NM_181466, NM_181467, NM_181468, NM_181469, NR_052022, NR_052023, NR_052024
UniProt ID P56537
Synonyms b(2)gcn; CAB; eIF-6; EIF3A; ITGB4BP; p27(BBP); p27BBP
Summary Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. provided by RefSeq, Jun 2012
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Documents
Resources
Other Versions
SKU Description Size Price
GA102481 EIF6 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 6 1 kit
$1,657.00
KN200568 EIF6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200568BN EIF6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200568LP EIF6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400568 EIF6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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