Syndecan 1 (SDC1) Human Gene Knockout Kit (CRISPR)

SKU
KN200419BN
SDC1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol Syndecan 1
Locus ID 6382
Components

KN200419G1, Syndecan 1 gRNA vector 1 in pCas-Guide CRISPR vector

KN200419G2, Syndecan 1 gRNA vector 2 in pCas-Guide CRISPR vector

KN200419BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001006946, NM_002997
UniProt ID P18827
Synonyms CD138; SDC; SYND1; syndecan
Summary The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA104338 SDC1 CRISPRa kit - CRISPR gene activation of human syndecan 1 1 kit
$1,657.00
KN200419 SDC1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200419LP SDC1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200419RB SDC1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400419 SDC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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