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elF2 alpha (EIF2S1) Human Gene Knockout Kit (CRISPR)

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SKU
KN200368RB
EIF2S1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "elF2 alpha or NM_004094"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol elF2 alpha
Locus ID 1965
Components

KN200368G1, elF2 alpha gRNA vector 1 in pCas-Guide CRISPR vector

KN200368G2, elF2 alpha gRNA vector 2 in pCas-Guide CRISPR vector

KN200368RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_004094
UniProt ID P05198
Synonyms EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A
Summary The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 PubMed 2948954).supplied by OMIM, Feb 2010
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Documents
Resources
Other Versions
SKU Description Size Price
GA101362 EIF2S1 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 2 subunit alpha 1 kit
$1,657.00
KN200368 EIF2S1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200368BN EIF2S1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200368LP EIF2S1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400368 EIF2S1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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