Human elF2 alpha (EIF2S1) activation kit by CRISPRa

SKU
GA101362
EIF2S1 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 2 subunit alpha
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol EIF2S1
Locus ID 1965
Components

GA101362G1, elF2 alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101362G2, elF2 alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101362G3, elF2 alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_004094
UniProt ID P05198
Synonyms EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A
Summary The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 PubMed 2948954).supplied by OMIM, Feb 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN200368 EIF2S1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200368BN EIF2S1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200368LP EIF2S1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200368RB EIF2S1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400368 EIF2S1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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