Human LC3B (MAP1LC3B) activation kit by CRISPRa

SKU GA113105

MAP1LC3B CRISPRa kit - CRISPR gene activation of human microtubule associated protein 1 light chain 3 beta

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MAP1LC3B
• Locus ID: 81631
• Components:

  GA113105G1, LC3B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA113105G2, LC3B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA113105G3, LC3B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_022818
• UniProt ID: Q9GZQ8
• Synonyms: ATG8F; LC3B; MAP1A/1BLC3; MAP1LC3B-a
• Summary: The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008]