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Human Dexras1 (RASD1) activation kit by CRISPRa

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SKU
GA109926
RASD1 CRISPRa kit - CRISPR gene activation of human ras related dexamethasone induced 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC205285 RASD1 (Myc-DDK-tagged)-Human RAS, dexamethasone-induced 1 (RASD1), transcript variant 1
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Other products for "RASD1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RASD1
Locus ID 51655
Components

GA109926G1, Dexras1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109926G2, Dexras1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109926G3, Dexras1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001199989, NM_016084
UniProt ID Q9Y272
Synonyms AGS1; DEXRAS1; MGC:26290
Summary This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Sep 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN405285 RASD1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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