Dexras1 (RASD1) Rabbit Polyclonal Antibody
Product Data | |
Application | ELISA, WB |
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Recommended Dilution | WB,1:200 - 1:2000 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
Reactivity | Human, Mouse |
Modification | Unmodified |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Buffer | Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 32kDa |
Gene Name | ras related dexamethasone induced 1 |
Database Link | |
Background | This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Synonyms | AGS1; DEXRAS1; MGC:26290 |
Reference Data |
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