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Human TMPRSS2 activation kit by CRISPRa

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SKU
GA104914
TMPRSS2 CRISPRa kit - CRISPR gene activation of human transmembrane serine protease 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA382628 TMPRSS2 Rabbit polyclonal Antibody
100 ul
$410.00
RC208677 TMPRSS2 (Myc-DDK-tagged)-Human transmembrane protease, serine 2 (TMPRSS2), transcript variant 2
10 ug
$457.00

Other products for "TMPRSS2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TMPRSS2
Locus ID 7113
Components

GA104914G1, TMPRSS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104914G2, TMPRSS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104914G3, TMPRSS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001135099, NM_005656
UniProt ID O15393
Synonyms PP9284; PRSS10
Summary This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. This protein also facilitates entry of viruses into host cells by proteolytically cleaving and activating viral envelope glycoproteins. Viruses found to use this protein for cell entry include Influenza virus and the human coronaviruses HCoV-229E, MERS-CoV, SARS-CoV and SARS-CoV-2 (COVID-19 virus). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Apr 2020
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Documents
Resources
Other Versions
SKU Description Size Price
KN208677 TMPRSS2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208677BN TMPRSS2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208677LP TMPRSS2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN208677RB TMPRSS2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN408677 TMPRSS2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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