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Human MDM2 activation kit by CRISPRa

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SKU
GA102858
MDM2 CRISPRa kit - CRISPR gene activation of human MDM2 proto-oncogene
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA801812 MDM2 mouse monoclonal antibody, clone OTI1E6 (formerly 1E6) 100 ul
$447.00
RC219518 MDM2 (Myc-DDK-tagged)-Human Mdm2 p53 binding protein homolog (mouse) (MDM2), transcript variant MDM2
10 ug
$686.00

Other products for "MDM2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MDM2
Locus ID 4193
Components

GA102858G1, MDM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102858G2, MDM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102858G3, MDM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001145336, NM_001145337, NM_001145339, NM_001145340, NM_001278462, NM_002392, NM_006878, NM_006879, NM_006880, NM_006881, NM_006882, NM_001367990
UniProt ID Q00987
Synonyms hdm2; HDMX; MGC5370; MGC71221
Summary This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. provided by RefSeq, Jun 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN419518 MDM2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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