Human CREB1 activation kit by CRISPRa

SKU GA100971

CREB1 CRISPRa kit - CRISPR gene activation of human cAMP responsive element binding protein 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CREB1
• Locus ID: 1385
• Components:

  GA100971G1, CREB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100971G2, CREB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100971G3, CREB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004379, NM_134442, NM_001320793, NR_135473
• UniProt ID: P16220
• Synonyms: CREB
• Summary: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]