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CD3E (NM_000733) Human Recombinant Protein

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SKU
TP790061
Purified recombinant protein of CD3-epsilon/delta heterodimers, with C-terminal His tag, secretory expressed in 293E cells, 20ug
Size:
20 ug
  $540.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Two DNA sequence from TrueORF clone, RC208276, RC210010,encoding the region of (ASP23-ASP126)CD3E-GGGGSVDGGGGG-(Phe22-105Ala)CD3D.
Tag C-His
Predicted MW 22.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 1 x PBS, pH 7.4, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000724
Locus ID 916
UniProt ID P07766
Cytogenetics 11q23.3
RefSeq Size 1534
RefSeq ORF 621
Synonyms IMD18; T3E; TCRE
Summary The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. provided by RefSeq, Jul 2008
Protein Categories ADC Targets, CD Markers, Immune system diseases, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway
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Other "CD3E" proteins (6)
SKU Description Size Price
PH308276 CD3E MS Standard C13 and N15-labeled recombinant protein (NP_000724) 10 ug
$3,360.00
LC400242 Lyophilized CD3E HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400242 Transient overexpression lysate of CD3e molecule, epsilon (CD3-TCR complex) (CD3E) (as WB positive control) 100 ug
$436.00
TP308276 Recombinant protein of human CD3e molecule, epsilon (CD3-TCR complex) (CD3E), 20 µg 20 ug
$867.00
TP700034 Recombinant protein of human CD3e molecule, epsilon (CD3-TCR complex) (CD3E), expressed in human cells 20 ug
$900.00
TP720690 Purified recombinant protein of Human CD3e molecule, epsilon (CD3-TCR complex) (CD3E) 10 ug
$275.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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