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CD3E (NM_000733) Human Recombinant Protein

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SKU
TP720690
Purified recombinant protein of Human CD3e molecule, epsilon (CD3-TCR complex) (CD3E)
Size:
10 ug 500 ug 50 ug
  $275.00
15 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Asp23-Asp126
Tag C-6His
Predicted MW 12.79 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reconstitution Method Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Shipping Ambient
Reference Data
RefSeq NP_000724
Locus ID 916
UniProt ID P07766
Cytogenetics 11q23.3
RefSeq Size 1534
RefSeq ORF 621
Synonyms IMD18; T3E; TCRE
Summary The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. provided by RefSeq, Jul 2008
Protein Categories ADC Targets, CD Markers, Immune system diseases, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway
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Other "CD3E" proteins (6)
SKU Description Size Price
PH308276 CD3E MS Standard C13 and N15-labeled recombinant protein (NP_000724) 10 ug
$3,360.00
LC400242 Lyophilized CD3E HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400242 Transient overexpression lysate of CD3e molecule, epsilon (CD3-TCR complex) (CD3E) (as WB positive control) 100 ug
$436.00
TP308276 Recombinant protein of human CD3e molecule, epsilon (CD3-TCR complex) (CD3E), 20 µg 20 ug
$867.00
TP700034 Recombinant protein of human CD3e molecule, epsilon (CD3-TCR complex) (CD3E), expressed in human cells 20 ug
$900.00
TP790061 Purified recombinant protein of CD3-epsilon/delta heterodimers, with C-terminal His tag, secretory expressed in 293E cells, 20ug 20 ug
$540.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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