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PD1 (PDCD1) (NM_005018) Human Recombinant Protein

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SKU
TP700198
Purified recombinant protein of Homo sapiens programmed cell death 1 (PDCD1), 25-167aa, with C-terminal DDK/His tag, expressed in HEK293 cells.
Size:
20 ug
  $900.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, RC210364, encoding the extracellular domain (Leu25 - Gln167) of human programmed cell death 1 (PDCD1)
Tag C-DDK/His
Predicted MW 31.65
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH 7.4, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_005009
Locus ID 5133
UniProt ID Q15116
Cytogenetics 2q37.3
RefSeq Size 2115
RefSeq ORF 864
Synonyms CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2
Summary Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. provided by RefSeq, Aug 2020
Protein Categories ADC Targets, Allergies and autoimmune diseases, CD Markers, Intracellular Proteins, Membrane Proteins, Nervous system Diseases
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), T cell receptor signaling pathway
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Other "PD1" proteins (18)
SKU Description Size Price
PH310364 PD-1 / PDCD1 MS Standard C13 and N15-labeled recombinant protein (NP_005009) 10 ug
$3,360.00
LC401555 Lyophilized PDCD1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401555 Transient overexpression lysate of programmed cell death 1 (PD-1 / PDCD1) (as WB positive control) 100 ug
$436.00
TP310364 Recombinant protein of human programmed cell death 1 (PDCD1), 20 µg 20 ug
$737.00
TP700199 Purified recombinant protein of Homo sapiens programmed cell death 1 (PD1/PDCD1), residues 25-167aa, with C-terminal Fc tag, expressed in HEK293 cells. 20 ug
$900.00
TP721292 Human PD1 Protein (C-His) 25 ug
$300.00
TP721293 Human PD1 Protein (C-His-Avi) 25 ug
$300.00
TP721294 Biotinylated Human PD1 Protein (C-His-Avi) 25 ug
$430.00
TP721295 PE Conjugated Human PD1 Protein (C-His) 25 ug
$430.00
TP721296 APC Conjugated Human PD1 Protein (C-His) 25 ug
$430.00
TP721297 Human PD1 Protein (C-Fc) 25 ug
$300.00
TP721298 Human PD1 Protein (C-Fc-Avi) 25 ug
$300.00
TP721299 Biotinylated Human PD1 Protein (C-Fc-Avi) 25 ug
$430.00
TP721300 PE Conjugated Human PD1 Protein (C-Fc) 25 ug
$430.00
TP721301 APC Conjugated Human PD1 Protein (C-Fc) 25 ug
$430.00
TP723948 Recombinant human PD-1 protein with C-terminal mouse Fc and 6×His tag 100 ug
$905.00
TP723998 Recombinant human PD-1 protein with C-terminal 6×His tag 100 ug
$695.00
TP723999 Recombinant human PD-1 protein with C-terminal human Fc and 6×His tag 100 ug
$905.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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