PD1 (PDCD1) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Human Fc and 6×His Tag |
| Predicted MW | The protein has a predicted molecular mass of 42.9 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining. |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Reconstitution Method | 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample. |
| Preparation | Affinity purification |
| Recommended Dilution | ELISA |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Shipping | Ambient |
| Reference Data | |
| Locus ID | 5133 |
| UniProt ID | Q15116 |
| Synonyms | PDCD1;PD1;CD279;SLEB2 |
| Summary | This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. |
| Protein Categories | ADC Targets, Allergies and autoimmune diseases, CD Markers, Intracellular Proteins, Membrane Proteins, Nervous system Diseases |
| Protein Families | ELISA |
| Protein Pathways | Cell adhesion molecules (CAMs), T cell receptor signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PD1" proteins (18)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH310364 | PD-1 / PDCD1 MS Standard C13 and N15-labeled recombinant protein (NP_005009) | 10 ug |
$3,360.00
|
|
| LC401555 | Lyophilized PDCD1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401555 | Transient overexpression lysate of programmed cell death 1 (PD-1 / PDCD1) (as WB positive control) | 100 ug |
$436.00
|
|
| TP310364 | Recombinant protein of human programmed cell death 1 (PDCD1), 20 µg | 20 ug |
$737.00
|
|
| TP700198 | Purified recombinant protein of Homo sapiens programmed cell death 1 (PDCD1), 25-167aa, with C-terminal DDK/His tag, expressed in HEK293 cells. | 20 ug |
$900.00
|
|
| TP700199 | Purified recombinant protein of Homo sapiens programmed cell death 1 (PD1/PDCD1), residues 25-167aa, with C-terminal Fc tag, expressed in HEK293 cells. | 20 ug |
$900.00
|
|
| TP721292 | Human PD1 Protein (C-His) | 25 ug |
$300.00
|
|
| TP721293 | Human PD1 Protein (C-His-Avi) | 25 ug |
$300.00
|
|
| TP721294 | Biotinylated Human PD1 Protein (C-His-Avi) | 25 ug |
$430.00
|
|
| TP721295 | PE Conjugated Human PD1 Protein (C-His) | 25 ug |
$430.00
|
|
| TP721296 | APC Conjugated Human PD1 Protein (C-His) | 25 ug |
$430.00
|
|
| TP721297 | Human PD1 Protein (C-Fc) | 25 ug |
$300.00
|
|
| TP721298 | Human PD1 Protein (C-Fc-Avi) | 25 ug |
$300.00
|
|
| TP721299 | Biotinylated Human PD1 Protein (C-Fc-Avi) | 25 ug |
$430.00
|
|
| TP721300 | PE Conjugated Human PD1 Protein (C-Fc) | 25 ug |
$430.00
|
|
| TP721301 | APC Conjugated Human PD1 Protein (C-Fc) | 25 ug |
$430.00
|
|
| TP723948 | Recombinant human PD-1 protein with C-terminal mouse Fc and 6×His tag | 100 ug |
$905.00
|
|
| TP723998 | Recombinant human PD-1 protein with C-terminal 6×His tag | 100 ug |
$695.00
|
|
Citations
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