IL1RA (IL1RN) (NM_000577) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 17.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000568 |
| Locus ID | 3557 |
| UniProt ID | P18510 |
| Cytogenetics | 2q14.1 |
| RefSeq Size | 1802 |
| RefSeq ORF | 477 |
| Synonyms | DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4 |
| Summary | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. provided by RefSeq, Aug 2020 |
| Protein Categories | Allergies and autoimmune diseases, Cytokines, Diabetes, Intracellular Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "IL1RA" proteins (15)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH302447 | IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_776215) | 10 ug |
$3,360.00
|
|
| PH312460 | IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_000568) | 10 ug |
$3,360.00
|
|
| PH318518 | IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_776214) | 10 ug |
$3,360.00
|
|
| LC403570 | Lyophilized IL1RN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC403571 | Lyophilized IL1RN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC406440 | Lyophilized IL1RN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC424628 | Lyophilized IL1RN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY403570 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY403571 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 4 (as WB positive control) | 100 ug |
$436.00
|
|
| LY406440 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY424628 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| TP302447 | Purified recombinant protein of Homo sapiens interleukin 1 receptor antagonist (IL1RN), transcript variant 4, 20 µg | 20 ug |
$737.00
|
|
| TP318518 | Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 1, 20 µg | 20 ug |
$737.00
|
|
| TP720025 | Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 3 | 10 ug |
$175.00
|
|
| TP760033 | Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 4, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug | 50 ug |
$270.00
|
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