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IL1RA (IL1RN) (NM_000577) Human Recombinant Protein

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SKU
TP720025
Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 3
  $175.00
7 Weeks*
Bulk/Customize

Frequently Bought Together (1)

TA803422 IL1RN mouse monoclonal antibody, clone OTI2B1 (formerly 2B1)
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Other products for "IL1RA or NM_000577"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Arg26-Glu177
Tag Tag Free
Predicted MW 17.3 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of PBS,PH7.4.
Bioactivity ED50 is 0.5 ng/ml as determined by the dose-dependent inhibition of IL-1 stimulation of D10S cells. Specific Activity of 2.0 x 106 IU/mg.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reconstitution Method Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Shipping Ambient
Reference Data
RefSeq NP_000568
Locus ID 3557
UniProt ID P18510
Cytogenetics 2q14.1
Synonyms DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4
Summary The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. provided by RefSeq, Aug 2020
Protein Categories Allergies and autoimmune diseases, Cytokines, Diabetes, Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
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Other "IL1RA" proteins (15)
SKU Description Size Price
PH302447 IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_776215) 10 ug
$3,360.00
PH312460 IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_000568) 10 ug
$3,360.00
PH318518 IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_776214) 10 ug
$3,360.00
LC403570 Lyophilized IL1RN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC403571 Lyophilized IL1RN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC406440 Lyophilized IL1RN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC424628 Lyophilized IL1RN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY403570 Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY403571 Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 4 (as WB positive control) 100 ug
$436.00
LY406440 Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY424628 Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 3 (as WB positive control) 100 ug
$436.00
TP302447 Purified recombinant protein of Homo sapiens interleukin 1 receptor antagonist (IL1RN), transcript variant 4, 20 µg 20 ug
$737.00
TP312460 Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 3, 20 µg 20 ug
$737.00
TP318518 Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 1, 20 µg 20 ug
$737.00
TP760033 Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 4, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
$270.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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