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Txn1 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN318506LP
Txn1 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

MR200355 Txn1 (Myc-DDK-tagged) - Mouse thioredoxin 1 (Txn1)
10 ug
$225.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "Txn1 or BC010756"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Txn1
Locus ID 22166
Components

KN318506G1, Txn1 gRNA vector 1 in pCas-Guide CRISPR vector

KN318506G2, Txn1 gRNA vector 2 in pCas-Guide CRISPR vector

KN318506LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_011660
UniProt ID P10639
Synonyms ADF; AW550880; Trx1; Txn
Summary Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
GA204501 Txn1 CRISPRa kit - CRISPR gene activation of mouse thioredoxin 1 1 kit
$1,657.00
KN318506 Txn1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN318506BN Txn1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN318506RB Txn1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN518506 Txn1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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