Mouse Txn1 activation kit by CRISPRa

SKU
GA204501
Txn1 CRISPRa kit - CRISPR gene activation of mouse thioredoxin 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Txn1
Locus ID 22166
Components

GA204501G1, Txn1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204501G2, Txn1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204501G3, Txn1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_011660
UniProt ID P10639
Synonyms ADF; AW550880; Trx1; Txn
Summary Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
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KN318506 Txn1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
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$1,657.00
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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