Slc22a17 Mouse Gene Knockout Kit (CRISPR)

SKU
KN315927LP
Slc22a17 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Slc22a17
Locus ID 59049
Components

KN315927G1, Slc22a17 gRNA vector 1 in pCas-Guide CRISPR vector

KN315927G2, Slc22a17 gRNA vector 2 in pCas-Guide CRISPR vector

KN315927LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_021551, NM_001360406
UniProt ID Q9D9E0
Synonyms 24p3R; 1700094C23Rik; AU041908; AW555662; Boct; BOIT
Summary Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
GA206358 Slc22a17 CRISPRa kit - CRISPR gene activation of mouse solute carrier family 22 (organic cation transporter), member 17 1 kit
$1,657.00
KN315927 Slc22a17 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN315927BN Slc22a17 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN315927RB Slc22a17 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN515927 Slc22a17 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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