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Mouse Slc22a17 activation kit by CRISPRa

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SKU
GA206358
Slc22a17 CRISPRa kit - CRISPR gene activation of mouse solute carrier family 22 (organic cation transporter), member 17
  $1,657.00
4 Weeks*

Other products for "Slc22a17"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Slc22a17
Locus ID 59049
Components

GA206358G1, Slc22a17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206358G2, Slc22a17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206358G3, Slc22a17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_021551, NM_001360406
UniProt ID Q9D9E0
Synonyms 24p3R; 1700094C23Rik; AU041908; AW555662; Boct; BOIT
Summary Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN315927 Slc22a17 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN315927BN Slc22a17 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN315927LP Slc22a17 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN315927RB Slc22a17 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN515927 Slc22a17 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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