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Pdgfra Mouse Gene Knockout Kit (CRISPR)

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SKU
KN313036LP
Pdgfra - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

MG211616 Pdgfra (tGFP-tagged) - Mouse platelet derived growth factor receptor, alpha polypeptide (Pdgfra), transcript variant 1
10 ug
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TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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Other products for "Pdgfra or BC053036"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Pdgfra
Locus ID 18595
Components

KN313036G1, Pdgfra gRNA vector 1 in pCas-Guide CRISPR vector

KN313036G2, Pdgfra gRNA vector 2 in pCas-Guide CRISPR vector

KN313036LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001083316, NM_011058, NR_144636
UniProt ID P26618
Synonyms AI115593; CD140a; Pdgfr-2
Summary This gene encodes a member of the receptor tyrosine kinase family of proteins. Binding of platelet-derived growth factor protein ligands to this receptor triggers receptor dimerization and autophosphorylation, resulting in the activation of several downstream signaling pathways. Signaling through the encoded receptor plays a role in gastrulation and the development of nearly all organ systems. Mice lacking a functional copy of this gene reportedly exhibit defects in lung, skeleton, testis and the central nervous system, and die soon after birth. Alternative splicing and intronic polyadenylation of gene transcripts have been implicated in muscle regeneration and fibrosis in adult mice. provided by RefSeq, Jan 2017
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Other Versions
SKU Description Size Price
GA203155 Pdgfra CRISPRa kit - CRISPR gene activation of mouse platelet derived growth factor receptor, alpha polypeptide 1 kit
$1,657.00
KN313036 Pdgfra - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN313036BN Pdgfra - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN313036RB Pdgfra - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN513036 Pdgfra - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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